Automated description from the Alliance of Genome Resources (Release 3.2)
Predicted to have oxoglutarate dehydrogenase (succinyl-transferring) activity and thiamine pyrophosphate binding activity. Involved in hematopoietic progenitor cell differentiation. Predicted to localize to mitochondrion. Used to study Charcot-Marie-Tooth disease axonal type 2Q and amino acid metabolic disorder. Human ortholog(s) of this gene implicated in 2-aminoadipic 2-oxoadipic aciduria and Charcot-Marie-Tooth disease axonal type 2Q. Orthologous to human DHTKD1 (dehydrogenase E1 and transketolase domain containing 1).