Automated description from the Alliance of Genome Resources (Release 4.0)
Predicted to enable histone binding activity; histone methyltransferase activity (H3-K4 specific); and transcription coactivator activity. Involved in histone methylation. Acts upstream of or within several processes, including eyelid development in camera-type eye; positive regulation of fibroblast proliferation; and single fertilization. Predicted to be located in nucleus. Predicted to be part of MLL3/4 complex. Is expressed in several structures, including eye; genitourinary system; limb; nervous system; and neural ectoderm. Human ortholog(s) of this gene implicated in Klatskin's tumor; Kleefstra syndrome 2; esophagus squamous cell carcinoma; and squamous cell carcinoma. Orthologous to human KMT2C (lysine methyltransferase 2C).