Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables S-adenosyl-L-methionine binding activity and histone H4K20 methyltransferase activity. Involved in positive regulation of isotype switching. Located in condensed chromosome, centromeric region. Is expressed in several structures, including genitourinary system; heart; hemolymphoid system gland; liver; and lung. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 51. Orthologous to human KMT5B (lysine methyltransferase 5B).