Automated description from the Alliance of Genome Resources (Release 3.2)
Predicted to have metal ion binding activity. Involved in animal organ development; embryonic digit morphogenesis; and morphogenesis of an epithelium. Localizes to basement membrane. Is expressed in several structures, including alimentary system; central nervous system; intraembryonic coelom; sensory organ; and skin. Used to study Fraser syndrome and isolated cryptophthalmia. Human ortholog(s) of this gene implicated in Fraser syndrome 2 and isolated cryptophthalmia. Orthologous to human FREM2 (FRAS1 related extracellular matrix 2).