Go Annotations as Summary Text (Tabular View) (GO Graph)

GO curators for mouse genes have assigned the following annotations to the gene product of Zdhhc9. (This text reflects annotations as of Wednesday, January 23, 2013.) MGI curation of this mouse gene is considered complete, including annotations derived from the biomedical literature as of February 2, 2010. If you know of any additional information regarding this mouse gene please let us know. Please supply mouse gene symbol and a PubMed ID.

---

Summary from NCBI RefSeq

[Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes an integral membrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein forms a complex with golgin subfamily A member 7 and functions as a palmitoyltransferase. This protein specifically palmitoylates HRAS and NRAS. Mutations in this gene are associated with X-linked mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, May 2010]

---

Summary text based on GO annotations supported by experimental evidence in other organisms

• From comparative sequence analysis (see table for details), MGI curators have determined that the gene product of Zdhhc9:
  • is located in the following cellular components:
    • cytoplasm
    • Golgi apparatus

---

Summary text based on GO annotations supported by structural data

• Zdhhc9 encodes a protein or proteins that contain the following InterPro domains: Zinc finger, DHHC-type, palmitoyltransferase, indicating that the gene product:
  • performs the following molecular functions:
    • zinc ion binding

---

Summary text for additional MGI annotations

• Automated translation to GO terms of SwissProt keywords that describe Zdhhc9 indicates that it:
  • performs the following molecular functions:
    • metal ion binding
    • transferase activity
    • transferase activity, transferring acyl groups
  • is located in the following cellular components:
    • endoplasmic reticulum
    • integral to membrane
    • membrane
• Annotations directly to biological process for the gene Zdhhc9 indicate that MGI curators have found no experimental data [literature] to support further annotation to this category at this time.

---

---

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

ISO Inferred from sequence orthology

ISA Inferred from sequence alignment

ISM Inferred from sequence model

NAS Non-traceable author statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

---