Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and methylated histone binding activity. Predicted to contribute to ATP-dependent activity, acting on DNA. Acts upstream of or within anterior/posterior pattern specification; embryonic placenta development; and endoderm development. Predicted to be located in several cellular components, including cell body; dendrite; and perinuclear region of cytoplasm. Predicted to be part of NURF complex. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; and retina. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with dysmorphic facies and distal limb anomalies. Orthologous to human BPTF (bromodomain PHD finger transcription factor).