Automated description from the Alliance of Genome Resources (Release 4.1.0)
Involved in limb development; nervous system development; and regulation of smoothened signaling pathway. Acts upstream of or within several processes, including cilium assembly; nervous system development; and skin development. Located in cytoplasm. Is expressed in central nervous system and retina. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy and orofaciodigital syndrome XVII. Orthologous to human INTU (inturned planar cell polarity protein).