Automated description from the Alliance of Genome Resources (Release 5.2.2)
Acts upstream of or within several processes, including brain morphogenesis; epithelial cilium movement involved in extracellular fluid movement; and sperm axoneme assembly. Located in Golgi apparatus; manchette; and sperm midpiece. Used to study primary ciliary dyskinesia. Human ortholog(s) of this gene implicated in spermatogenic failure 43. Orthologous to human SPEF2 (sperm flagellar 2).