Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable enzyme binding activity and ubiquitin ligase-substrate adaptor activity. Involved in positive regulation of autophagy; positive regulation of regulatory T cell differentiation; and regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including autophagy; negative regulation of neuron apoptotic process; and neural tube development. Located in axoneme; cytosol; and phagocytic vesicle. Is active in cytoplasm and nucleus. Is expressed in main olfactory bulb. Orthologous to human AMBRA1 (autophagy and beclin 1 regulator 1).