Automated description from the Alliance of Genome Resources (Release 3.0)
Exhibits transcription factor binding activity; ubiquitin protein ligase binding activity; and ubiquitin-protein transferase regulator activity. Involved in several processes, including negative regulation of DNA-binding transcription factor activity; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; and regulation of myeloid leukocyte differentiation. Predicted to localize to cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; heart valve; metanephros; and retina. Orthologous to human TRIB1 (tribbles pseudokinase 1).