Automated description from the Alliance of Genome Resources
Exhibits methylcytosine dioxygenase activity. Involved in several processes, including animal organ development; cellular protein modification process; and hematopoietic stem cell homeostasis. Predicted to localize to the nucleus. Human ortholog(s) of this gene implicated in acute myeloid leukemia; chronic myelomonocytic leukemia; myelodysplastic syndrome; and myeloproliferative neoplasm. Is expressed in several structures, including brain; early conceptus; future brain; and genitourinary system. Orthologous to human TET2 (tet methylcytosine dioxygenase 2).