Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits methylcytosine dioxygenase activity. Involved in several processes, including animal organ development; cellular protein modification process; and hematopoietic stem cell homeostasis. Predicted to localize to nucleus. Is expressed in several structures, including brain; early conceptus; future brain; and genitourinary system. Human ortholog(s) of this gene implicated in acute myeloid leukemia; chronic myelomonocytic leukemia; myelodysplastic syndrome; and myeloproliferative neoplasm. Orthologous to human TET2 (tet methylcytosine dioxygenase 2).