Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits ATP binding activity; MAP kinase kinase kinase activity; and magnesium ion binding activity. Involved in several processes, including embryonic digit morphogenesis; intracellular signal transduction; and protein phosphorylation. Localizes to cytoplasm and nucleus. Is expressed in heart; limb; and urinary system. Used to study split hand-foot malformation. Human ortholog(s) of this gene implicated in centronuclear myopathy 6 with fiber-type disproportion. Orthologous to human MAP3K20 (mitogen-activated protein kinase kinase kinase 20).