Automated description from the Alliance of Genome Resources (Release 5.2.0)
Predicted to enable 5'-3' DNA helicase activity and chromatin binding activity. Acts upstream of or within reciprocal meiotic recombination; seminiferous tubule development; and spermatogenesis. Predicted to be located in cytoplasm; nuclear membrane; and nucleoplasm. Predicted to be part of BRCA1-B complex. Predicted to be active in nucleus. Is expressed in brain ventricular layer; cochlea; and rest of cerebellum marginal layer. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group J; breast cancer; colorectal cancer; and thrombocytopenia. Orthologous to human BRIP1 (BRCA1 interacting helicase 1).