Automated description from the Alliance of Genome Resources
Exhibits histone demethylase activity (H3-K9 specific). Involved in histone H3-K36 demethylation; histone H3-K9 demethylation; and negative regulation of histone H3-K9 trimethylation. Localizes to the nuclear pericentric heterochromatin. Human ortholog(s) of this gene implicated in breast cancer; colorectal cancer; malignant peripheral nerve sheath tumor; and stomach cancer. Is expressed in several structures, including early conceptus; genitourinary system; heart; nervous system; and sensory organ. Orthologous to human KDM4B (lysine demethylase 4B).