Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables histone H3K36 demethylase activity and histone H3K9 demethylase activity. Involved in brain development. Acts upstream of or within chromatin remodeling. Part of pericentric heterochromatin. Is expressed in several structures, including early conceptus; nervous system; reproductive system; sensory organ; and urinary system. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder; breast cancer; colorectal cancer; malignant peripheral nerve sheath tumor; and stomach cancer. Orthologous to human KDM4B (lysine demethylase 4B).