Automated description from the Alliance of Genome Resources (Release 3.0)
Predicted to contribute to GTPase activator activity. Involved in several processes, including negative regulation of cellular metabolic process; regulation of intracellular signal transduction; and regulation of protein modification process. Predicted to colocalize with cell-cell contact zone and midbody. Used to study Birt-Hogg-Dube syndrome and nonpapillary renal cell carcinoma. Human ortholog(s) of this gene implicated in Birt-Hogg-Dube syndrome; colorectal cancer; primary spontaneous pneumothorax; and renal cell carcinoma. Is expressed in several structures, including embryo ectoderm; exocrine gland; extraembryonic component; limb bud; and optic cup. Orthologous to human FLCN (folliculin).