Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits SH2 domain binding activity and phosphatidylinositol phosphate binding activity. Involved in several processes, including animal organ development; osteoblast fate commitment; and podosome assembly. Localizes to cytoplasm and podosome. Is expressed in several structures, including branchial arch; central nervous system; heart; jaw; and skeleton. Used to study glaucoma and otitis media. Human ortholog(s) of this gene implicated in Frank-Ter Haar syndrome. Orthologous to human SH3PXD2B (SH3 and PX domains 2B).