Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits protein kinase binding activity. Predicted to be involved in several processes, including amyloid-beta clearance by transcytosis; endocytosis; and negative regulation of hyaluronan biosynthetic process. Localizes to several cellular components, including clathrin-coated pit; photoreceptor ribbon synapse; and presynaptic endocytic zone membrane. Is expressed in 8-cell stage embryo; brain; placenta; and unsegmented mesenchyme. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 56. Orthologous to human CLTC (clathrin heavy chain).