Automated description from the Alliance of Genome Resources
Predicted to have CARD domain binding activity. Predicted to be involved in several processes, including positive regulation of NF-kappaB transcription factor activity; positive regulation of protein phosphorylation; and tumor necrosis factor-mediated signaling pathway. Predicted to localize to the cytoplasm. Used to study psoriasis 2. Human ortholog(s) of this gene implicated in pityriasis rubra pilaris and psoriasis 2. Is expressed in gut; nose; and vibrissa. Orthologous to human CARD14 (caspase recruitment domain family member 14).