Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have identical protein binding activity. Involved in several processes, including animal organ development; non-motile cilium assembly; and photoreceptor cell maintenance. Localizes to MKS complex; centriolar satellite; and photoreceptor cell cilium. Predicted to colocalize with gamma-tubulin complex. Used to study Joubert syndrome 5; Leber congenital amaurosis 10; cystic kidney disease; and visceral heterotaxy. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 14; Joubert syndrome 5; Leber congenital amaurosis 10; Meckel syndrome 4; and Senior-Loken syndrome. Orthologous to human CEP290 (centrosomal protein 290).