Automated description from the Alliance of Genome Resources
Predicted to have identical protein binding activity. Involved in several processes, including non-motile cilium assembly; photoreceptor cell maintenance; and protein transport. Localizes to the centriolar satellite and cilium. Predicted to colocalize with the gamma-tubulin complex. Used to study Joubert syndrome 5; Leber congenital amaurosis 10; cystic kidney disease; and visceral heterotaxy. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 14; Joubert syndrome 5; Leber congenital amaurosis 10; Meckel syndrome 4; and Senior-Loken syndrome. Orthologous to human CEP290 (centrosomal protein 290).