Automated description from the Alliance of Genome Resources
Predicted to have Rab GTPase binding activity; phospholipid binding activity; and protein homodimerization activity. Involved in several processes, including adiponectin-activated signaling pathway; regulation of defense response; and regulation of vesicle-mediated transport. Localizes to the early phagosome membrane; macropinosome; and ruffle membrane. Is expressed in several structures, including alimentary system; autopod; forebrain; neural retina; and ventricular layer. Orthologous to human APPL2 (adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2).