Automated description from the Alliance of Genome Resources (Release 3.2)
Predicted to have several functions, including calmodulin binding activity; protein kinase binding activity; and tubulin binding activity. Involved in establishment of mitotic spindle orientation; negative regulation of centriole replication; and nervous system development. Localizes to centrosome and mitotic spindle pole. Predicted to colocalize with gamma-tubulin ring complex. Is expressed in central nervous system and retina. Used to study microcephaly. Human ortholog(s) of this gene implicated in Seckel syndrome; microcephaly; and primary autosomal recessive microcephaly 3. Orthologous to several human genes including CDK5RAP2 (CDK5 regulatory subunit associated protein 2).