Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable identical protein binding activity and pyrroline-5-carboxylate reductase activity. Predicted to be involved in several processes, including L-proline biosynthetic process; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway; and regulation of mitochondrial membrane potential. Predicted to act upstream of or within amino acid biosynthetic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; ear; genitourinary system; and skeleton. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IIB and autosomal recessive cutis laxa type IIIB. Orthologous to human PYCR1 (pyrroline-5-carboxylate reductase 1).