Automated description from the Alliance of Genome Resources (Release 4.1.0)
Enables histone methyltransferase activity (H3-K4 specific) and histone methyltransferase activity (H3-K9 specific). Acts upstream of or within several processes, including negative regulation of intracellular signal transduction; reproductive structure development; and tarsal gland development. Predicted to be located in Golgi apparatus and nucleoplasm. Is expressed in early conceptus; inner cell mass; oocyte; and ureter. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 52. Orthologous to human ASH1L (ASH1 like histone lysine methyltransferase).