Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable cytokine binding activity and cytokine receptor activity. Predicted to contribute to interleukin-12 receptor binding activity; interleukin-23 binding activity; and interleukin-23 receptor activity. Predicted to be involved in several processes, including positive regulation of defense response to virus by host; regulation of cytokine production; and response to type II interferon. Predicted to act upstream of or within leukocyte mediated immunity and receptor signaling pathway via JAK-STAT. Predicted to be located in plasma membrane. Predicted to be part of interleukin-23 receptor complex. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); bone disease (multiple); inflammatory bowel disease (multiple); pulmonary hypertension; and systemic scleroderma. Orthologous to human IL23R (interleukin 23 receptor).