Go Annotations as Summary Text (Tabular View) (GO Graph)

GO curators for mouse genes have assigned the following annotations to the gene product of Slc5a2. (This text reflects annotations as of Tuesday, July 8, 2014.)

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Summary from NCBI RefSeq

[Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. The encoded protein is the major cotransporter involved in glucose reabsorption in the kidney. Mutations in this gene are associated with renal glucosuria. [provided by RefSeq, Sep 2009]

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Summary text based on GO annotations supported by experimental evidence in mouse

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Summary text based on GO annotations supported by experimental evidence in other organisms

• From comparative sequence analysis (see table for details), MGI curators have determined that the gene product of Slc5a2:
  • participates in the following biological processes:
    • glucose transport
    • hexose transmembrane transport
    • sodium ion transmembrane transport
  • performs the following molecular functions:
    • glucose:sodium symporter activity
  • is located in the following cellular components:
    • brush border membrane
    • extracellular vesicular exosome
    • integral component of membrane

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Summary text based on GO annotations supported by structural data

• Slc5a2 encodes a protein or proteins that contain the following InterPro domains: indicating that the gene product:
  • participates in the following biological processes:
    • transmembrane transport
    • transport
  • performs the following molecular functions:
    • transporter activity
  • is located in the following cellular components:
    • membrane

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Summary text for additional MGI annotations

• Automated translation to GO terms of SwissProt keywords that describe Slc5a2 indicates that it:
  • participates in the following biological processes:
    • carbohydrate transport
    • ion transport
    • sodium ion transport
    • transport
  • performs the following molecular functions:
    • symporter activity
  • is located in the following cellular components:
    • membrane

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References

1. . () , :. (PubMed:)

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Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

ISO Inferred from sequence orthology

ISA Inferred from sequence alignment

ISM Inferred from sequence model

NAS Non-traceable author statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

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