Automated description from the Alliance of Genome Resources (Release 3.0)
Exhibits mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Involved in positive regulation of retrograde protein transport, ER to cytosol; trimming of terminal mannose on C branch; and ubiquitin-dependent ERAD pathway. Localizes to integral component of endoplasmic reticulum membrane. Is expressed in embryo and liver. Orthologous to human EDEM1 (ER degradation enhancing alpha-mannosidase like protein 1).