Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity; pre-mRNA intronic binding activity; and snRNA binding activity. Predicted to be involved in cellular response to lipopolysaccharide; cellular response to tumor necrosis factor; and spliceosomal tri-snRNP complex assembly. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in nucleus. Predicted to be part of U2-type spliceosomal complex and spliceosomal snRNP complex. Is expressed in several structures, including central nervous system; gonad; gut; sensory organ; and spleen. Used to study retinitis pigmentosa 13. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 13. Orthologous to human PRPF8 (pre-mRNA processing factor 8).