Automated description from the Alliance of Genome Resources
Predicted to contribute to guanyl-nucleotide exchange factor activity. Involved in several processes, including melanocyte differentiation; positive regulation of natural killer cell activation; and secretion of lysosomal enzymes. Predicted to localize to the BLOC-3 complex and cytoplasmic vesicle. Used to study Hermansky-Pudlak syndrome 1 and platelet storage pool deficiency. Human ortholog(s) of this gene implicated in Hermansky-Pudlak syndrome 1 and oculocutaneous albinism. Orthologous to human HPS1 (HPS1 biogenesis of lysosomal organelles complex 3 subunit 1).