Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits DNA-directed DNA polymerase activity. Involved in double-strand break repair via alternative nonhomologous end joining; negative regulation of double-strand break repair via homologous recombination; and somatic hypermutation of immunoglobulin genes. Predicted to localize to cytoplasm and nucleus. Is expressed in embryo; heart; spleen; and testis. Orthologous to human POLQ (DNA polymerase theta).