Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables protein serine/threonine kinase activity. Involved in several processes, including execution phase of necroptosis; hematopoietic or lymphoid organ development; and positive regulation of necroptotic process. Acts upstream of or within with a positive effect on non-canonical NF-kappaB signal transduction. Acts upstream of or within positive regulation of intrinsic apoptotic signaling pathway; positive regulation of protein deacetylation; and regulation of reactive oxygen species metabolic process. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; immune system; male reproductive gland or organ; primitive streak; and turbinate bone primordium. Orthologous to human RIPK3 (receptor interacting serine/threonine kinase 3).