Automated description from the Alliance of Genome Resources (Release 5.3.0)
Enables semaphorin receptor activity. Involved in several processes, including negative regulation of neuron apoptotic process; nervous system development; and semaphorin-plexin signaling pathway. Acts upstream of or within several processes, including circulatory system development; dichotomous subdivision of terminal units involved in salivary gland branching; and positive regulation of protein binding activity. Located in axon; cell body; and plasma membrane. Is active in glutamatergic synapse. Is expressed in several structures, including cardiovascular system; genitourinary system; liver; nervous system; and spleen. Used to study DiGeorge syndrome. Orthologous to human PLXND1 (plexin D1).