Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits semaphorin receptor activity. Involved in several processes, including circulatory system development; dichotomous subdivision of terminal units involved in salivary gland branching; and endothelial cell migration. Localizes to integral component of plasma membrane. Is expressed in several structures, including cardiovascular system; genitourinary system; liver; nervous system; and spleen. Used to study DiGeorge syndrome. Orthologous to human PLXND1 (plexin D1).