Automated description from the Alliance of Genome Resources
Contributes to chloride channel activity. Predicted to be involved in cellular ion homeostasis and chloride transport. Localizes to the basolateral plasma membrane; integral component of plasma membrane; and protein-containing complex. Used to study Bartter disease type 4a. Human ortholog(s) of this gene implicated in Bartter disease; Bartter disease type 4a; and sensorineural hearing loss. Is expressed in central nervous system; inner ear; and metanephros. Orthologous to human BSND (barttin CLCNK type accessory beta subunit).