Automated description from the Alliance of Genome Resources
Exhibits gap junction channel activity. Involved in cell-cell signaling and response to toxic substance. Localizes to the gap junction and myelin sheath. Used to study hypomyelinating leukodystrophy 2. Human ortholog(s) of this gene implicated in hereditary lymphedema IC; hereditary spastic paraplegia 44; hypomyelinating leukodystrophy 2; and lymphedema. Orthologous to human GJC2 (gap junction protein gamma 2).