Automated description from the Alliance of Genome Resources (Release 5.0.0)
Enables transmembrane transporter binding activity. A structural constituent of presynaptic active zone. Involved in neurotransmitter secretion; positive regulation of gene expression; and regulation of nervous system process. Acts upstream of or within calcium ion-regulated exocytosis of neurotransmitter; regulation of long-term neuronal synaptic plasticity; and regulation of membrane potential. Located in inhibitory synapse; postsynaptic density; and vesicle. Is active in GABA-ergic synapse; glutamatergic synapse; and presynaptic active zone cytoplasmic component. Human ortholog(s) of this gene implicated in cone-rod dystrophy 7. Orthologous to human RIMS1 (regulating synaptic membrane exocytosis 1).