Automated description from the Alliance of Genome Resources
Exhibits voltage-gated calcium channel activity. Contributes to mechanosensitive ion channel activity. Involved in several processes, including auditory receptor cell development; detection of mechanical stimulus involved in sensory perception of sound; and vestibular reflex. Localizes to the external side of plasma membrane and stereocilium tip. Used to study autosomal dominant nonsyndromic deafness 36 and autosomal recessive nonsyndromic deafness 7. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 36; autosomal recessive nonsyndromic deafness 7; and sensorineural hearing loss. Is expressed in sensory organ and skeleton. Orthologous to human TMC1 (transmembrane channel like 1).