Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits GTPase activator activity. Involved in several processes, including T cell activation; membrane raft polarization; and myeloid dendritic cell activation involved in immune response. Predicted to localize to cytoplasm; cytoskeleton; and membrane. Is expressed in central nervous system; paraxial mesenchyme; and retina. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human DOCK2 (dedicator of cytokinesis 2).