Automated description from the Alliance of Genome Resources
Exhibits serine-type endopeptidase inhibitor activity. Involved in several processes, including negative regulation of blood vessel endothelial cell migration; regulation of blood coagulation; and regulation of transcription from RNA polymerase II promoter in response to iron. Localizes to the endolysosome and phagolysosome membrane. Human ortholog(s) of this gene implicated in thrombophilia and thrombosis. Orthologous to human HRG (histidine rich glycoprotein).