Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits ubiquitin protein ligase activity. Involved in several processes, including common myeloid progenitor cell proliferation; positive regulation of protein polyubiquitination; and protein destabilization. Localizes to SCF ubiquitin ligase complex. Is expressed in several structures, including craniocervical region bone; esophagus; lung; pituitary gland; and sensory organ. Orthologous to human FBXO4 (F-box protein 4).