Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable signaling adaptor activity. Involved in several processes, including establishment of T cell polarity; negative regulation of activated T cell proliferation; and synaptic vesicle cycle. Acts upstream of or within several processes, including nervous system development; post-anal tail morphogenesis; and wound healing. Located in several cellular components, including basolateral plasma membrane; immunological synapse; and myelin sheath abaxonal region. Is expressed in several structures, including embryo mesenchyme; genitourinary system; gut; hair follicle; and nervous system. Used to study prostate cancer. Orthologous to human SCRIB (scribble planar cell polarity protein).