Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits gated channel activity; phospholipid scramblase activity; and protein homodimerization activity. Involved in several processes, including calcium activated phospholipid scrambling; inorganic ion transmembrane transport; and positive regulation of transport. Localizes to integral component of plasma membrane. Is expressed in several structures, including alimentary system; nervous system; respiratory system; sensory organ; and viscerocranium. Human ortholog(s) of this gene implicated in Scott syndrome; ankylosing spondylitis; and inflammatory bowel disease. Orthologous to human ANO6 (anoctamin 6).