Automated description from the Alliance of Genome Resources
Exhibits ion gated channel activity; phospholipid scramblase activity; and protein homodimerization activity. Involved in several processes, including calcium activated phospholipid scrambling; inorganic ion transmembrane transport; and positive regulation of transport. Predicted to localize to the chloride channel complex; cytosol; and plasma membrane. Human ortholog(s) of this gene implicated in Scott syndrome; ankylosing spondylitis; and inflammatory bowel disease. Orthologous to human ANO6 (anoctamin 6).