Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits single-stranded DNA 5'-3' exodeoxyribonuclease activity. Involved in hematopoietic progenitor cell differentiation; phagocytosis; and regulation of cytokine production involved in inflammatory response. Localizes to several cellular components, including cytoplasmic vesicle; endoplasmic reticulum membrane; and trans-Golgi network membrane. Is expressed in brain and hemolymphoid system. Used to study systemic lupus erythematosus. Orthologous to human PLD4 (phospholipase D family member 4).