Automated description from the Alliance of Genome Resources
Exhibits ubiquitin-protein transferase activity. Contributes to ubiquitin protein ligase activity. Involved in several processes, including SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; cellular protein modification process; and negative regulation of NIK/NF-kappaB signaling. Localizes to the SCF ubiquitin ligase complex; cytosol; and nucleus. Orthologous to human FBXW11 (F-box and WD repeat domain containing 11).