Automated description from the Alliance of Genome Resources (Release 4.0)
Exhibits ubiquitin-protein transferase activity. Contributes to ubiquitin protein ligase activity. Involved in several processes, including cellular protein metabolic process; negative regulation of NIK/NF-kappaB signaling; and positive regulation of circadian rhythm. Localizes to SCF ubiquitin ligase complex; cytosol; and nucleus. Is expressed in cap mesenchyme; early tubule; ovary; and testis. Orthologous to human FBXW11 (F-box and WD repeat domain containing 11).