Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits histone methyltransferase activity. Involved in gene expression. Predicted to localize to nucleoplasm and protein-containing complex. Is expressed in several structures, including 1st branchial arch; blood; heart; sensory organ; and yolk sac. Used to study dilated cardiomyopathy 1A. Human ortholog(s) of this gene implicated in mixed phenotype acute leukemia. Orthologous to human DOT1L (DOT1 like histone lysine methyltransferase).