Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; phosphatidylinositol-3-phosphate phosphatase activity; and phosphatidylinositol-4-phosphate phosphatase activity. Acts upstream of or within several processes, including negative regulation of myelination; nervous system development; and phosphatidylinositol metabolic process. Predicted to be located in endosome membrane and lipid droplet. Predicted to be active in intracellular membrane-bounded organelle. Predicted to colocalize with recycling endosome. Is expressed in nervous system; nucleus pulposus; thymus primordium; and vibrissa. Used to study Charcot-Marie-Tooth disease type 4J and Yunis-Varon syndrome. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4J; Yunis-Varon syndrome; amyotrophic lateral sclerosis type 11; and bilateral parasagittal parieto-occipital polymicrogyria. Orthologous to human FIG4 (FIG4 phosphoinositide 5-phosphatase).