Automated description from the Alliance of Genome Resources (Release 4.0)
Predicted to have phosphatidylinositol bisphosphate phosphatase activity; phosphatidylinositol-3-phosphatase activity; and phosphatidylinositol-4-phosphate phosphatase activity. Involved in several processes, including negative regulation of myelination; nervous system development; and phosphatidylinositol metabolic process. Predicted to colocalize with Golgi apparatus; endoplasmic reticulum; and recycling endosome. Is expressed in cerebral cortex; ganglia; nucleus pulposus; thymus primordium; and vibrissa. Used to study Charcot-Marie-Tooth disease type 4J and Yunis-Varon syndrome. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4J; Yunis-Varon syndrome; and amyotrophic lateral sclerosis type 11. Orthologous to human FIG4 (FIG4 phosphoinositide 5-phosphatase).