Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have Rho guanyl-nucleotide exchange factor activity. Predicted to be involved in several processes, including negative regulation of stress fiber assembly; protein localization to cell-cell junction; and regulation of Rho protein signal transduction. Predicted to localize to apical part of cell; cytosol; and plasma membrane. Is expressed in brain; dermis; epidermis; and metanephros. Human ortholog(s) of this gene implicated in retinitis pigmentosa. Orthologous to human ARHGEF18 (Rho/Rac guanine nucleotide exchange factor 18).