Automated description from the Alliance of Genome Resources (Release 5.2.2)
Predicted to enable cAMP response element binding protein binding activity. Involved in entrainment of circadian clock by photoperiod and positive regulation of CREB transcription factor activity. Acts upstream of or within several processes, including energy homeostasis; memory; and negative regulation of membrane hyperpolarization. Located in cytoplasm and nucleus. Is expressed in limb and limb mesenchyme. Used to study major depressive disorder. Orthologous to human CRTC1 (CREB regulated transcription coactivator 1).