Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity. Involved in B cell chemotaxis. Predicted to be located in lipid droplet. Is expressed in several structures, including alimentary system; bladder; facial bone primordium; heart; and liver and biliary system. Human ortholog(s) of this gene implicated in congenital bile acid synthesis defect 1 and intrahepatic cholestasis. Orthologous to human HSD3B7 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7).