Automated description from the Alliance of Genome Resources (Release 4.0)
Is predicted to contribute to GTPase activator activity. Involved in cellular response to amino acid starvation; negative regulation of TORC1 signaling; and regulation of autophagy. Located in cytosol and perinuclear region of cytoplasm. Predicted to be part of Cul3-RING ubiquitin ligase complex and GATOR1 complex. Predicted to be active in lysosomal membrane. Is expressed in branchial arch; genitourinary system; limb; and peripheral nervous system. Human ortholog(s) of this gene implicated in focal epilepsy. Orthologous to human DEPDC5 (DEP domain containing 5, GATOR1 subcomplex subunit).