Automated description from the Alliance of Genome Resources (Release 3.0)
Predicted to have RNA polymerase II core promoter sequence-specific DNA binding activity; SUMO ligase activity; and transcription corepressor activity. Predicted to be involved in several processes, including negative regulation of transcription initiation from RNA polymerase II promoter; negative regulation of transforming growth factor beta receptor signaling pathway; and regulation of histone modification. Predicted to colocalize with histone methyltransferase complex. Is expressed in brain; early conceptus; gonad; and metanephros. Orthologous to human ZNF451 (zinc finger protein 451).