Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables cytoskeletal protein binding activity; integrin binding activity; and protein homodimerization activity. Involved in actin filament bundle assembly. Located in several cellular components, including Z disc; fascia adherens; and ruffle. Colocalizes with stress fiber. Is expressed in brain; heart; heart ventricle; and testis. Human ortholog(s) of this gene implicated in platelet-type bleeding disorder 15. Orthologous to human ACTN1 (actinin alpha 1).